INTRAOPERATION PROCEEDING OF IMPLANTATION LVAD IN DIFERENT COAGULATION GRUP OF PATIENTS
DOI:
https://doi.org/10.32782/2411-9164.24.1-10Keywords:
left ventricle assist device (LVAD), anticoagulant targeted therapy (ATT), surgical, infectious, renal, pulmonary, ischemic-hemorrhagic complicationsAbstract
The work was carried out within the framework of a bilateral agreement on scientific cooperation between the department of Anesthesiology&Intensive Care in National Medical Academy of Post-Graduate Education Named After P.L. Shupik and the Silesian Center for Heart Diseases (Poland). Introduction. That work is probe of analisis response and complications e introperation LVAD patients on some intraoperative infusion and transfusion tactic fifty patients with implanted devices for mechanical support of the left ventricle, left ventricle assist device, LVAD, in the Silesian Heart Disease Center (Śląski Centrum Chorób Serca – SCCS), Poland. Patients were divided into two groups, a control group receiving classical anticoagulation targeted therapy (ATT), which included the most controlled monotherapy with heparin, after reaching the target values of APTT, the addition and transition to monotherapy with warfarin until reaching the target INR and ASA, and the main, research group, who received an alternative ATT consisting of the previous one with the addition of P2Y12-receptor blockers and Xa-factors. The result of the work demonstrated the benefit of the modified anticoagulant treatment scheme against the classical approach with clear confirmation by correlation- regression indicators of a significant degree of reliability. A prognostic assessment of the dynamic state of the patient was also proposed to reduce clinical complications after this intervention.
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